Helical chiral 2,2'-bipyridine N-monoxides as catalysts in the enantioselective propargylation of aldehydes with allenyltrichlorosilane.
نویسندگان
چکیده
A highly enantioselective synthesis of homopropargylic alcohols is achieved by using the new helical chiral 2,2'-bipyridine N-monoxide catalyst and allenyltrichlorosilane. This method can be further extended to the enantio- and regioselective propargylation of N-acylhydrazones.
منابع مشابه
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ورودعنوان ژورنال:
- Organic letters
دوره 13 7 شماره
صفحات -
تاریخ انتشار 2011